Doctors are using these types of transplants more often, to expand the use of transplantation as an effective cancer treatment. Cells from a parent, child, brother, or sister are not always a perfect match for a patient's HLA type, but they are a 50% match. Parent-child transplant and haplotype mismatched transplant. Cancer centers around the world use cord blood. The umbilical cord connects a fetus to its mother before birth. In this type of transplant, stem cells from umbilical cord blood are used. If your health care team cannot find a donor match, there are other options. In this condition, the healthy transplant cells attack your cells. If your donor’s proteins closely match yours, you are less likely to get a serious side effect called graft-versus-host disease (GVHD). Siblings from the same parents are often the best match, but another family member or an unrelated volunteer can be a match too. A match is a healthy donor whose blood proteins, called human leukocyte antigens (HLA), closely match yours. This is the main way ALLO transplants work to treat the cancer.įinding a “donor match” is a necessary step for an ALLO transplant. This is when the new stem cells recognize and destroy cancer cells that are still in the body. Many people have a “graft-versus-cancer cell effect” during an ALLO transplant. The donor's stem cells are given to the patient after the patient has chemotherapy and/or radiation therapy.

Stem cells for an allogenic transplant come from another person, called a donor. This process is also called an AUTO transplant or stem cell rescue.Īllogenic transplant. That's why doctors remove, or rescue, your stem cells from your blood or bone marrow before the cancer treatment begins.Īfter chemotherapy, the stem cells are returned to your body, restoring your immune system and your body's ability to produce blood cells and fight infection. This type of treatment can damage your stem cells and your immune system. Sometimes, cancer is treated with a high-dose, intensive chemotherapy or radiation therapy treatment. Stem cells for an autologous transplant come from your own body. The 2 main types are:Īutologous transplant. There are different types of bone marrow/stem cell transplants. What are the different types of transplant? This restores your body's ability to create the red blood cells, white blood cells, and platelets it needs. They fight pathogens, which are the viruses and bacteria that can make you sick.Ī bone marrow/stem cell transplant is a medical procedure by which healthy stem cells are transplanted into your bone marrow or your blood.

White blood cells are a part of your immune system. They also take carbon dioxide to your lungs so that it can be exhaled. Red blood cells carry oxygen throughout your body. These blood cells are very important and each one has a different job: When hematopoietic stem cells are damaged, they may not become red blood cells, white blood cells, and platelets. Hematopoietic stem cells are also found in the blood that is moving throughout your body. Hematopoietic stem cells are stem cells that turn into blood cells.īone marrow is soft, spongy tissue in the body that contains hematopoietic stem cells. There are several kinds of stem cells and they are found in different parts of the body at different times.Ĭancer and cancer treatment can damage your hematopoietic stem cells. Stem cells are special cells that can make copies of themselves and change into the many different kinds of cells that your body needs. What are stem cells? What is bone marrow? Transplantation can be used to treat certain types of cancer, such as leukemia, myeloma, and lymphoma, and other blood and immune system diseases that affect the bone marrow. The replacement cells can either come from your own body or from a donor.Ī bone marrow transplant is also called a stem cell transplant or, more specifically, a hematopoietic stem cell transplant.

A bone marrow transplant is a medical treatment that replaces your bone marrow with healthy cells.

Stem cell transplant